Publications

New Peptide-Based Pharmacophore Activates 20S Proteasome.

Osmulski PA, Karpowicz P, Jankowska E, Bohmann J, Pickering AM, Gaczyńska M.


Molecules. 2020 Mar 22;25(6):1439. doi: 10.3390/molecules25061439. PMID: 32235805; PMCID: PMC7145288.

Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models

Chocron ES, Munkácsy E, Kim HS, Karpowicz P, Jiang N, Van Skike CE, DeRosa N, Banh AQ, Palavicini JP, Wityk P, Kalinowski L, Galvan V, Osmulski PA, Jankowska E, Gaczynska M, Pickering AM.


Science Advances. 2022 Jun 10;8(23):eabk2252. doi: 10.1126/sciadv.abk2252. Epub 2022 Jun 8. PMID: 35675410; PMCID: PMC9177073.

Proteasome Augmentation Mitigates Age-Related Cognitive
Decline in Mice

Parker D, Davidson K, Osmulski PA, Gaczynska M, Pickering AM.


Aging Cell 2025 In Press